Wednesday, 15th February Lorne Infection and Immunity 2023

• Vaginal microbiome and HIV susceptibility - Gilda Tachedjian

• Role of iBALT in Tuberculosis - Shabaana Khader
• Programmed cell death crosstalk in a monogenetic inflammatory disease - James Vince
• ADS032, the first dual NLRP1 and NLRP3 inflammasome inhibitor for the treatment of infectious and inflammatory diseases - Ashley Mansell
• MLKL mutation causes defective immune response during bacterial infection - Sarah E Garnish
• Probing the molecular basis of curbing TLR4-driven inflammatory responses - Thomas E Schultz
• IFNλ1 utilises interferon alpha/beta receptor 2 to induce signalling and anti-viral defence in lung epithelial cells - Nicky de Weerd

• Predicting immunogenicity using human tonsil organoids - Lisa Wagar
• High-throughput characterization of antibody responses in SARS-CoV-2 infection and vaccination - Amy Chung
• Exploiting the tropism of viral vectored vaccines for optimal induction of liver resident T cells and long-term protection against malaria - Alexandra Spencer
• Systems immunology of T follicular helper cells reveals impaired BCL6 function in ageing. - Danika L Hill
• Butyrophilin 3A1 interacts with the Vγ9Vδ2⁺ T cell receptor - Tom S Fulford
• T cell immunity in cytomegalovirus infection - Annette Oxenius

Lorne Central

54-56 Mountjoy Parade, Lorne VIC 3232

• Strategic and scientific contributions of human challenge trials for vaccine development: facts versus fantasy - Yara N Abo
• Activation of the NLRP3 inflammasome by Hendra Virus C-protein - Kristian T Barry
• Features of a novel sheep model of ALI/ARDS induced by pulmonary instillation of live Streptococcus pneumoniae - Rob Bischof
• Antimalarial compounds the 2-Anilino 4-Amino substituted quinazolines, are irresistible and promiscuous. - Hayley Bullen
• An integrated atlas of innate immune cell responses to activating stimuli reveals time-, dose- and ligand-dependent axes of inflammation. - Suzanne Butcher
• Establishing human small intestinal monolayers to study EPEC infection - Eva Chan
• Smith-specific TCR-Tregs successfully treat lupus nephritis in a humanised model of disease - Rachel MY Cheong
• Treating influenza A exacerbations – the case for pirfenidone over glucocorticoids - Julia Chitty
• Clade-specific gastrointestinal microbiota modulates epithelial endoplasmic reticulum stress response - Michelle Chonwerawong
• Helicobacter pylori extracellular vesicles contain urease and catalase which promote bacterial survival - Nina Colon
• Decoding resident immune cell communication - Caleb Dawson
• Cumulative vaccine take of RV3-BB rotavirus vaccine observed in Indonesian infants regardless of histo-blood group antigen status - Celeste M Donato
• The Helicobacter pylori virulence factor, Tipa, is carried by bacterial extracellular vesicles to the nuclear compartment of host cells. - Jack Emery
• Mapping of critical dengue virus-host interactions by APEX proximity labelling to reveal future antiviral drug targets.  - Siena Centofanti
• Do anti-LPS antibodies to patient microbiota associate with worse outcomes in Crohn's disease? - Wenkang Feng
• Characterising the role of NKG7 in CD4⁺ and CD8⁺ T cells during malaria - Teija Frame
• Distribution of phenotypic antimicrobial resistance in the gastrointestinal microbiome. - Emily L Gulliver
• COVID-19 in Brazil: Antibody Fc-dependent Mechanisms in Natural and Vaccine-Induced Immunity - Alexander Harris
• Antibody Protection of Pseudomonas aeruginosa Isolates from Bloodstream Infections - Sarah M Hickson
• Developing a reproducible and defined protocol to differentiate human induced pluripotent stem cells into colon epithelium as a model to study colonic innate immunity and inflammatory and infectious diseases - Hani Hosseini Far
• Defining the fine specificity of antibody responses to polymorphic and conserved epitopes of the lead malaria vaccine antigen: Plasmodium falciparum circumsporozoite protein - Alessia Hysa
• Modulation of ICAM-1 on vaginal epithelial cells by a microbiome bioactive and HIV transmission - Brianna Jesaveluk
• Characterisation of the DNA associated with bacterial membrane vesicles from the human gut microbiota - Ella L. Johnston
• Exploiting rabies virus hijacking of neuronal synapse formation - Stephanie J Keating
• Molecular regulation of Clec9A-mediated damage recognition and antigen presentation in dendritic cells - Mireille H Lahoud
• HIV-1 infected macrophages can be made susceptible to Antibody Dependent Cellular Cytotoxicity by small molecule CD4 mimetics - Annemarie Laumaea
• Recall, breadth and longevity of humoral immunity following Omicron BA.1 and BA.2 breakthrough infection - Wen Shi Lee
• Temporal kinetics of functional antibody responses following naturally acquired Plasmodium vivax malaria infections - Rhea Longley
• The interaction between Dynamin 3 and Kelch 13 in Plasmodium falciparum - Richard R Marais
• Investigating the effects of short chain fatty acids on fungal pathogen host interactions - Christopher J McCrory
• Characterisation of an essential dynamin-like protein in the malaria parasite Plasmodium falciparum - Emma McHugh
• Trafficking of the RhopH complex in malaria parasites - Joyanta Modak
• Targeting virus-STAT interactions to generate novel attenuated ‘live’ vaccines - Gregory W Moseley
• Development and evaluation of novel immunotherapeutics for EBV lymphomas in preclinical models - Swathi Muralidhar
• Mouse GBP1 is detrimental for the host during Burkholderia thailandensis infection - Garrett Ng
• A novel approach to uncover cryptic cases of immunodeficiency - Tahereh Noori
• Age, chorioamnionitis, and the innate immune system in preterm infants - Josephine C Owen
• BCL-2 and BCL-XL dynamically regulate LPS-primed macrophage survival in the absence of BCL2A1 - Ashlyn P Pascoe
• The role of gut macrophages in gut epithelial barrier formation - Sophia Piryaei
• Enhanced stability of the SARS CoV-2 spike glycoprotein trimer following modification of an alanine cavity in the protein core - Christine Langer
• The Plasmodium falciparum artemisinin resistance protein Kelch 13 is required for formation of normal cytostomes and parasite feeding - Stuart A Ralph
• Infectious Disease Research: It’s time to think differently - Tiffany Pang
• Gasdermin D deficiency limits the severity of pulmonary disease during influenza A virus infection - Sarah Rosli
• Lipid nanoparticle-mediated delivery of RNA therapeutics to treat Mycobacterium tuberculosis infection - Jan Schaefer
• Streptococcus pneumoniae potently kill mesothelial and mesothelioma cells in a strain dependent manner - Hui Juin Shak
• The role of BTN3A1 in regulating αβ T cell responses - Kezia Christilla Singgih
• Characterisation of CD1c-restricted T cells recognising mycobacterial lipids - Caroline Soliman
• Understanding the innate immune response to Group A Streptococcus pili - Risa Takahashi
• Single-cell RNAseq analysis of HIV reservoir cells from viremic and virally-suppressed individuals living with HIV - Sushama Telwatte
• MLKL deficiency protects against sterile inflammation and immunosenescence in aged mice - Emma C. Tovey Crutchfield
• Covalent probe reveals Ubc13 interactome in the malaria parasite - Anna Truong
• Functional IL-37 receptor cell surface expression on immune cell subsets in health and disease by flow cytometry  - Holly K Ung
• Structural and functional characterisation of a novel gasdermin protein - Joshua von Ameln
• Pilus tip protein AP1 essential for Group A Streptococcus adhesion to the tonsil epithelium - Alisha M Wilson
• Kinetics of the innate antiviral response of equine peripheral mononuclear cells in response to Ross River virus - Ka Yuen